PDB (Protein Data Bank)

Assalamualaikum,
Ok,here I would like to share with you what we have learned in computer in science about PDB.

So,what is PDB stand for??

The Protein Data Bank (PDB; http://www.rcsb.org/pdb/ ) is the single worldwide archive of structural data of biological macromolecules. This paper describes the goals of the PDB, the systems in place for data deposition and access, how to obtain further information, and near-term plans for the future development of the resource.

Firstly, what is protein data bank?

• A repository for 3-D biological macromolecular structure
• It includes proteins, nucleic acids and viruses
• it is used by biologists and biochemists to represent the proteins in structure form.
• PDB is an important resourse for research in science sectors including pharmaceutical, biotechnology and   biomedical science.

How the structure of a chemical looks like by using PDB?

From the example of the trypsine structure below,you can see how beautiful the structure of a small chemical that cannot be seen by our naked eyes. Protein Data Bank helps a lot in reseach industry for the improvement of new technology.

The above diagram is a stucture of trypsin.

The table below shows the details about trypsin. This data also can be obtained from the website which I have stated earlier in this topic. For more structures and data, you may find from that website.

Tittle	2 PTC THE GEOMETRY OF THE REACTIVE SITE AND OF THE PEPTIDE GROUPS IN TRYPSIN, TRYPSINOGEN AND ITS COMPLEXES WITH INHIBITORS
Compound	2 Polymers Molecule: BETA TRYPSIN Polymer:1 Type:Protein Length: 223 Chains: E Organism: Bos taurus
Authors	Huber, R
Exp.method	X-RAY DIFFRACTION with resolution of 1.90
Classification	Proteinase Inhibitor
Primary citation	Structure of form III crystals of bovine pancreatic trypsin inhibitor.  (1987) J.Mol.Biol. 198: 469-480

In short, it is proven that Protein Data Bank is very important for showing 3-D biological macromolecular structure of a chemical and the data about it that is useful for the scientists, lecturers and students for learning process and for research.